Hydroxyzine, sold under the brand names Atarax (as hydrochloride) and Vistaril (as pamoate) among others, is an antihistamine medication. It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). Hydroxyzine is used to treat anxiety, tension, itching from allergic skin reactions, and sedation. Learn about doses, side effects, interactions, and uses Overview: Hydroxyzine is an antihistamine that is used for certain types of anxiety, itching due to allergic conditions, to help you relax before and after general anesthesia, or for nausea and. Hydroxyzine is an antihistamine used to treat allergy symptoms and more. Learn how to use hydroxyzine for anxiety, its dosage, and potential side effects. Hydroxyzine is used for the short-term treatment of nervousness and tension that may occur with certain mental/mood disorders. Learn about side effects, drug interactions, dosages, warnings, and more. Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. Detailed Hydroxyzine dosage information for adults and children. Includes dosages for Anxiety, Nausea/Vomiting, Sedation and more; plus renal, liver and dialysis adjustments.